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Computational Nuclear Medicine

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Dr. Barbara Geist

Research interests:

  • Quantification of dynamic data, Kinetic Modeling
  • Organ connectomes, Network Analyses
  • Stress determination and effect in PET imaging
  • Quantification of metabolic changes in PET imaging

 

 

Contact:

Clemens Spielvogel, PhD

Research interests:

  • Clinical and biomedical applications of artificial intelligence and computational imaging
  • Opportunistic risk markers
  • Computational cardiovascular imaging
  • Cardiac amyloidosis

 

Links:

Contact:

Song Xue, PhD

Research interests:

  • Ultra-low dose PET imaging with AI
  • Individualized dosimetry for radiopharmaceutical therapy
  • Biomarkers identification for prognosis and therapy response
  • AI-driven radiopharmaceutical discovery and development

Links:

Contact:

Dipl.-Ing. David Haberl

Research interests:

  • Medical Imaging and Computational Image Analysis
  • Deep Learning, Computer Vision

Links:

Zewen Jiang, MD

Research interests:

  • Multimodality medical images and whole-body PET/CT
  • Non-small cell lung cancer and tumor organoids

Links:

Jing Ning, MD

Research interests:

  • Nuclear medicine and molecular imaging in oncology

  • Multi-omics data and analysis

Links:

Josef Yu, MD

Research interests:

  • Investigation of cachexia using PET/CT and inter-organ connection
  • Chronic stress in cancer

Links:

Michael Beyerlein

  • Study program: Clinical medicine (Dr. med)
  • Research topic: Stress biomarkers in breast cancer

Christopher Eseroglou, MSc

  • Study program: Master Computational Science
  • Research topic: Computational methods for the quantification of artherosclerosis and arterial inflammation in patients undergoing FDG PET/CT

Markus Köfler, BSc

  • Study program: Master Data Science
  • Research topics: Machine learning and segmentation in cardiac amyloidosis characterization

Iustin Tibu

  • Study program: Clinical medicine (Dr. med)
  • Research topic: Stress biomarkers in lung cancer

Publications (selection)

1. Spielvogel, C. P. et al. Diagnosis and prognosis of abnormal cardiac scintigraphy uptake suggestive of cardiac amyloidosis using artificial intelligence: a retrospective, international, multicentre, cross-tracer development and validation study. Lancet Digit Health 6, e251–e260 (2024).

2. Haberl, D. et al. Multicenter PET image harmonization using generative adversarial networks. Eur. J. Nucl. Med. Mol. Imaging 51, 2532–2546 (2024).

3. Ning, J. et al. A novel assessment of whole-mount Gleason grading in prostate cancer to identify candidates for radical prostatectomy: a machine learning-based multiomics study. Theranostics 14, 4570–4581 (2024).

4. Geist, B. K. et al. In vivo assessment of safety, biodistribution, and radiation dosimetry of the [18F]Me4FDG PET-radiotracer in adults. EJNMMI Res. 14, 46 (2024).

5. Spielvogel, C. P. et al. Radiogenomic markers enable risk stratification and inference of mutational pathway states in head and neck cancer. Eur. J. Nucl. Med. Mol. Imaging 50, 546–558 (2023).

6. Geist, B. K. et al. A methodological investigation of healthy tissue, hepatocellular carcinoma, and other lesions with dynamic 68Ga-FAPI-04 PET/CT imaging. EJNMMI Phys. 8, 8 (2021).

7. Papp, L. et al. Supervised machine learning enables non-invasive lesion characterization in primary prostate cancer with [68Ga]Ga-PSMA-11 PET/MRI. Eur. J. Nucl. Med. Mol. Imaging 48, 1795–1805 (2021).

8. Geist, B. K. et al. Comparison of different kinetic models for dynamic 18F-FDG PET/CT imaging of hepatocellular carcinoma with various, also dual-blood input function. Phys. Med. Biol. 65, 045001 (2020).